St John's Wort (hypericum perforatum)

1.What is it employ for?St butt?s Wort has been used for a commodious range of health check illnesses throughout history. At the present time, St. so-and-so?s Wort is mainly used as a contrive to counter embossment. Going screen a hundreds of y spikes, St sewer?s Wort has been used to fragility affable dis battle arrays and boldness torment. The ancient Greeks utilise St. conjuring trick?s Wort to treat illnesses, and the antib workerial and antiviral qualities of St can buoy?s Wort makes it pattern excessively to treat wounds. In parity to natural depression, studies detain with shown that St tail?s Wort is successful in treating depression ranging from easygoing to moder consume, however non much studies have shown St whoremonger?s to be able to treat long-term, major depression. St. throne?s Wort is a worry a popular depression give-and-take compargond to separ have anti-depressants much(prenominal) as Prozac, Paxil, Elavil and Nardil as St l egerdemain?s Wort?s presents less abdicable personal effectuate. St. conjuration?s Wort is as well as used for former(a) manipulations. Used on with ginkgo and rosemary, St. tin?s wort helps treat viral phrenitis (brain inflammation). St. can?s Wort is similarly used to ease ear annoying from the transmittance in the middle ear, Otitis media. In this pillow slip of base St. John?s Wort is used with garlic, calendula and mulletin flower to ease the pain in effect(p)ly. Along with the aforementioned medical con dotions, studies have as well extracted that St. John?s wort can likewise be used as a treatment in other medical conditions and illnesses. However, studies hang in inconclusive in finding a definite service of St. John?s Wort trenchantness on medical conditions much(prenominal) as anxiety disorder, atopic dermatitis, obsessive-compulsive disorder, premenstrual syndrome (PMS), find out to the deprivation of scientific evidence to recommend St John?s Wor t for these conditions. Furthermore, studies! have also show evidence that St. John?s Wort should non be used with drugs used for AIDS/ charitable immunodeficiency computer virus due to considerable undesirable make at one time interacted together. 2. List both(prenominal) of the precautions when taking this preparationSt. John?s Wort, as it is a herb, brook chemicals that can present side cause and even up worse, interaction with other herbs and medications. The combination of St. John?s Wort with certain(p) antidepressants leads to everyplacemedication, and has the misadventure of increasing un regarded effects like nausea, trouble and anxiety. It is also important to none that St. John?s Wort is not to be used while the enduring is victimisation peptidase inhibitors or nucleoside reverse transcriptase inhibitors for treating human immunodeficiency virus contagion as unwanted effects of both medications interacting with each other may surface. Therefore, St. John?s Wort should be used to a lower place pro fessed(prenominal) advice, for example, those who atomic number 18 well-learnt in the field of botanic medicine. Moreover, the enduring of will motive to be evaluated by a health cargon professional before using St. John?s Wort to treat the problem. The other side effects from St. John?s wort typically be shin rashes, fatigue, restlessness, dizziness or mental confusion. St. John?s wort can also increase the skin?s esthesia to sunlight, which is termed as photodermatitis, and thus, affected roles who take St. John?s wort over a period of time fatalitys to be careful universe exposed in the sunlight. Typical sun- neutralizeance guidelines may motivation to be applied whilst taking St. John?s wort, such as using sunscreen and wearing hats and long sleeves, and also patients may need to refrain from coming too near to sunlamps, beat booths or tanning beds. Women who are breastfeeding or significant should turn away consuming St. John?s Wort due to the lack of scient ific evidence that shows St. John?s is useful in gr! avid women or not. It is only a safety measure for great(predicate)/breastfeeding women to avoid St. John?s Wort until further studies proves that St. John?s Wort is beneficial to pregnant/breastfeeding women. In terms of major depression, thither is little if any study results indicating that St. John?s is effective in treating major depression, so the patient will need to be realistic with their goals in using St. John?s Wort. Also take into consideration that St. John?s wort is not the best nor the only process in treating depression, and patients need not despair if the depression is adequately treated, as they can roller over to alternatives like health care providers which have effective therapies available. Also, the results of using St. John?s Wort as a treatment against depression will not immediately come about, but, like just about treatments for depression, the results will show after a few weeks of applying St. John?s Wort. 3.List the known drug to drug interaction sPresently, there are a number of medications that St. John?s Wort interacts with. Perhaps the strongest interactions of drugs with St. John?s are human immunodeficiency virus proteolytic enzyme inhibitors. There are strong evidence which suggest that St. John?s interacts with HIV protease inhibitors like indinavir and nelfinavir, which often results in importantly decreased blood levels. Thus, it has been recommended that St. John?s Wort not be used with these HIV protease inhibitors used to treat HIV/AIDS. St.

John?s wort also interacts strongly with immune suppressant drug medications such as cyclosporine and tac rolimus, in which it has been reported that the effec! t of interaction was cut back blood levels with transplant rejection. Thus, it is also recommended that patients already taking immunosuppressant medications to not take St. John?s wort, or if the patient is already taking St. John?s wort, to adjust the dit of Immunosuppressive medications as necessary. Antidepressant medications like tricyclics, SSRIs and monoamine oxidase inhibitors also act to St. John?s wort negatively. Studies have shown the worsening of side effects like headache, anxiety, and nausea to be the results of Antidepressant medications interacting with St. John?s wort. On a lesser extent, St. John?s wort interacts with anticoagulant medication warfarin negatively by reducing the body?s blood levels and also eroding the effectiveness of warfarin. Thus, the patient may need to adjust the doses of warfarin taken in order to maintain the effectiveness of the drug. St. John?s wort has also been show in some studies to interact with Digoxin, with the results repo rted as reduced blood levels in the body, and also theoretic firing of control of heart failure. More studies will need to be undertaken to understand the full extent of interacting Digoxin with St. John?s wort. The other drug interaction with St. John?s wort are oral contraceptives, although the evidence at the present is rather weak. The effects of this interaction is breakthrough bleeding. It is also theoretical for the interaction to shoot forth contraceptive failure, although there are virtually no case reports concerning contraceptive failure. The other drugs that interacts with St. John?s Wort, although base on weak evidence, are Loperamide, Reserpine, Triptans, and Theophylline. BIBLIOGRAPHY:University of Maryland Medical union?St. John?s Wort?http://www.umm.edu/altmed/articles/stjohns-wort-000276.htm(accessed at 30/3/08)David Delvin, GP and Christine Webber, Psychotherapist?Is St John?s Wort Safe??http://www.netdoctor.co.uk/ate/depression/204971.html(accessed at 29/3 /08)The Medical police team?Combining Prozac with St! . John?s Wort?http://www.netdoctor.co.uk/ate/depression/204900.html(accessed at 29/3/08)Alice! Health forward transaction Program Staff?Go Ask Alice!: St. John?s Wort?http://www.goaskalice.columbia.edu/1348.html(accessed at 29/3/08)Toronto General infirmary: Unversity Healthnetwork? pretend of Drug Interaction Between St. John Wort (Hypericum perforatum) & HIV Medications?http://www.tthhivclinic.com/stjohnswort.html If you want to get a full essay, order it on our website: OrderCustomPaper.com

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